TABLE 1.
Clinical and Pathological Features of Study Subjects
| Subjects/ Classificat ion |
Age, years | Sex | Brain Weight, g |
MMSE | CERAD Classificat ion |
Braak Score |
PMI, hours |
|---|---|---|---|---|---|---|---|
| NCI | 88 | F | 1,240 | 29 | Probable | V | 3 |
| NCI | 95 | F | 1,130 | 27 | Possible | 0 | 2 |
| NCI | 80 | M | 1,430 | 27 | None | IV | 3 |
| NCI | 70 | M | 1,530 | 30 | None | I | 3 |
| NCI | 90 | F | 1,110 | 29 | None | I | 4 |
| NCI | 89 | F | 1,210 | 30 | Probable | IV | 2 |
| NCI | 84 | F | 940 | 30 | None | III | 5 |
| NCI | 88 | F | 1,070 | 29 | None | III | 3 |
| NCI | 84 | F | 1,230 | 30 | None | 0 | 3 |
| NCI | 92 | M | 1,220 | 28 | Probable | 0 | 3.5 |
| Mean ± SD |
86.0 ± 7.1 | 1,211 ± 170 |
28.9 ± 1.2 | 3.1 ± 0.9 | |||
| MCI | 91 | F | 1,130 | 26 | Probable | V | 2.0 |
| MCI | 93 | F | 1,050 | 27 | Probable | III | 2.5 |
| MCI | 87 | M | 1,200 | 24 | Definite | IV | 3.5 |
| MCI | 88 | F | 1,080 | 17 | Definite | V | 5.0 |
| MCI | 99 | F | 930 | 20 | Possible | V | 2.0 |
| MCI | 84 | M | 1,350 | 24 | Probable | IV | 4.0 |
| MCI | 89 | M | 1,330 | 26 | Definite | I | 3.0 |
| MCI | 88 | F | 1,130 | 28 | Definite | III | 3.0 |
| Mean ± SD |
90.3 ± 4.8 | 1,150 ± 141 |
24.0 ± 3.7 | 3.1 ± 1.0 | |||
| mAD | 93 | M | 1,230 | 21 | Definite | IV | 4.0 |
| mAD | 89 | F | 1,190 | 20 | None | IV | 3.5 |
| mAD | 77 | F | 1,190 | 23 | Definite | V | 3.0 |
| mAD | 82 | M | 1,090 | 25 | Definite | II | 2.0 |
| Mean ± SD |
85.3 ± 7.1 | 1,175 ± 60 |
22.3 ± 2.2 | 3.1 ± 0.9 | |||
| AD | 84 | M | 1,150 | 14 | Definite | VI | 4.5 |
| AD | 86 | F | 1,030 | 7 | Definite | VI | 3.0 |
| AD | 68 | M | 1,380 | 11 | Probable | II | 4.0 |
| AD | 90 | M | 1,200 | 12 | Definite | VI | 3.0 |
| AD | 86 | F | 1,070 | 14 | Definite | VI | 5.0 |
| AD | 78 | F | 1,080 | 11 | Definite | VI | 3.5 |
| AD | 82 | F | 1,260 | 13 | Definite | VI | 4.5 |
| AD | 85 | M | 1,020 | 15 | Probable | VI | 3.0 |
| AD | 73 | M | 1,130 | 16 | Definite | VI | 2.0 |
| Mean ± SD |
81.3 ± 7.1 | 1,147 ± 117 |
12.6 ± 2.7 | 3.6 ± 1.0 |
AD, Alzheimer disease; CERAD, Consortium to Establish a Registry for Alzheimer Disease; F, female; M, male; mAD, mild Alzheimer disease; MCI, mild cognitive impairment; MMSE, Mini Mental State Examination score; NCI, no cognitive impairment; PMI, postmortem interval.