Fig. 1.
The effects of Apo2L/TRAIL alone on surgical specimens of 2 patients’ colon adenocarcinomas grown in SCID mice. Mice bearing tumors of 50 mm3 starting volume were treated with intraperitoneal injections of 500 μg Apo2L/TRAIL daily for 14 days. a The growth of tumor 11124 was significantly inhibited by Apo2L/TRAIL (• = Control; ▪= Apo2L/TRAIL; p < 0.001). b The growth of tumor 11501 was not significantly inhibited (• = Control; ▪ = Apo2L/TRAIL). Horizontal bar indicates one cycle of treatment. Error bars = standard deviation, n = 6.