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. Author manuscript; available in PMC: 2010 Feb 23.
Published in final edited form as: Restor Neurol Neurosci. 2009;27(3):163–179. doi: 10.3233/RNN-2009-0467

Fig. 2.

Fig. 2

Sex differences in Ischemic Brain Injury are Unaffected by Diabetes and Hypertension. Hypoxia-ischemia (HI) was induced in male and female db/db mice, a genetic model of Type II diabetes, by combined common carotid artery ligation and hypoxia, and tissue damage assessed by hematoxylin and eosin staining. Focal cerebral ischemia was induced in age-matched male and female stroke prone spontaneously hypertensive rats (SHR-SP) rats by MCA occlusion for 2 hours, and infarct size was measured at 24 hours by triphenyl-tetrazolium chloride (TTC).