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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Clin Psychol Rev. 2010 Feb;30(1):12–24. doi: 10.1016/j.cpr.2009.08.009

Table 1.

Studies of the effect of smoking cessation on drinking urges and alcohol use.

Study Participants and Design Findings
Studies of smoking as a strategy to cope with urges to drink
Monti et al. (1995) A questionnaire study of 116 smokers in
residential SUD treatment for alcohol
problems.
58% of subjects reoported that they have
smoked to cope with drinking urges, but only
20% reported that smoking decreases their
urge to drink.
Asher et al. (2003) A questionnaire study of 96 smokers in
residential treatment for alcohol problems.
Subjects were enrolled in a smoking
intervention clinical trial but were not
required to quit.
41% of subjects said quitting smoking during
AOD treatment would make it harder to stay
sober; however, only 13% said that their
urges to drink would be too strong to resist if
they quit smoking.
Rohsenow et al. (2005) A questionnaire study of 160 smokers in
residential SUD treatment for alcohol
problems. Subjects were enrolled in a
smoking intervention clinical trial but were
not required to quit.
30% of subjects said quitting smoking during
alcohol treatment would make it harder to
stay sober; smoking to cope with AOD urges
did not predict AOD use (i.e., relapse) three
months after the start of SUD treatment.
Kalman et al. (2001) A questionnaire study of 80 smokers in
residential SUD treatment for alcohol
problems. Subjects were enrolled in a
smoking cessation clinical trial.
29% of subjects said that smoking would
help them cope with an urge to drink during
periods of sobriety; among these participants,
only 8% said it would help them to cope “a
lot”.
Kalman et al. (unpublished) A questionnaire study of 130 smokers in
residential SUD treatment for alcohol
problems. Subjects were enrolled in a
smoking cessation clinical trial. One week
following their quit day, subjects were
asked to report on the effect of quitting
smoking on their effort to abstain from
alcohol.
5% of subjects said that quitting smoking
made trying to abstain from alcohol a “little
more difficult;” none said it made trying to
abstain "a lot more difficult;" The reamining
subjects said either that quitting made
abstaining from alcohol either a little or a lot
easier (45%) or that it had no effect (50%).
Studies of the effect of smoking deprivation on urges to drink
Cooney et al. (2003) 40 alcohol-dependent, heavy smokers in
SUD treatment for alcohol problems (mean
number of days of abstinence was 16.8).
Subjects participated in two laboratory
sessions: one following 34 hours of
smoking deprivation.and one following ad
libitum smoking. In both sessions, subjects
were exposed to alcohol and neutral (water)
cues.
Urge to drink was not affected by nicotine
deprivation during alcohol cue exposure.
Colby et al. (2004) College-age moderate to heavy drinking
smokers participated in two laboratory
sessions: one following 5 hours of smoking
deprivation.and one following ad libitum
smoking. In both sessions, subjects were
exposed to alcohol and neutral (water)
cues.
Subjects did not report any increase in urge
to drink or psycho-physiological reactions
(i.e., salivation, heart rate) during alcohol cue
exposure vs. exposure to a neutral (water)
cue. Smoking deprivation did not influence
the amount of alcohol consumed immediately
following the cue reactivity procedure.
Cooney et al. (2007) 102 subjects participated iin smoking
cessation treatment in a SUD program and
provided EMA data for 14 days following
discharge from the program. Subjects
recorded their urge to drink immediately
prior to smoking, 5 minutes after the onset
of smoking, and at random prompts.
Frequency of drinking urges among smoking
abstinent participants did not differ from
those who returned to smoking following
concurrent alcohol and tobacco treatment;
smoking modestly increased urge to drink
Palfai et al. (2000) In a 2 × 2 factorial design, 56 nontreatment-
seeking moderate to heavy drinking
smokers participated in one of four
conditions: (1) exposure to smoking cues
following 6 hours of smoking deprivation;
(2) exposure to smoking cues following ad
libitum smoking; (3) exposure to neutral
cues following 6 hours of smoking
deprivation; (4) exposure to neutral cues
following 6 hours of smoking deprivation.
Smoking deprivation significantly increased
urge to drink and alcohol consumption.
Alcohol expectancies partially mediated the
relationship between smoking deprivation
and alcohol consumption. Cue exposure
condition did not affect results.

Note. AOD = alcohol and other drug use. EMA = ecological momentary assessment. SUD = substance use disorder.