Table 7.

Comparison of the features of two optical scattering methods for sensing photothermal bubbles.

Detection method	Pros	Cons
Time-resolved image mode	High sensitivity	Requires precise focusing due to small size of PTB
	Shows 2D location of the PTB	Saturates when PTB size reaches some threshold
	Pixel image amplitude is PTB size-dependent
	Pixel image amplitude can be amplified by increasing
	pulse fluence
Response mode	Allows detection of the PTB in 3D volume regardless	Relatively low sensitivity
	of its specific position	Signal duration slightly depends upon the number
	Signal duration is PTB size-dependent	of the PTBs in the aperture of the probe beam
	Does not saturate when PTB size reaches
	some threshold
	Allows detection of other PT phenomena such as
	heating of the bulk media

PT: Photothermal; PTB: Photothermal bubble.