Table 4.

Adverse Events

Event	Protocol; No. (%) of Patients*
	2006 Standard Protocol (n = 50)	2006 Lower-Target Protocol (n = 50)	1996 Study1 (n = 50)
Major bleeding episode	0	1 (2)	5 (10)
Recurrence of DVT or PE	0	0	2/43 (5)
Arterial thromboembolic disease	0	0	0
Death
Due to major bleeding	0	1 (2)	0
Due to DVT or PE	1 (2)*	0	1 (2)
Other cause	1 (2)	0	2 (4)

DVT = deep vein thrombosis, PE = pulmonary embolism.

^*Exact cause of death not confirmed.