Table 1.

IgG isotypes induced by CD40 ligation in response to NP-Ficoll^a)

Recipients	NP-specific IgG isotypes (ng/ml)
	IgG₁	IgG_2a	IgG₃
Naive	n.d.^b)	61 ± 17	6,729 ± 887
TI Immune	6,120 ± 5,316	2,550 ± 1803	7,257 ± 1700
Anti-CD40	203 ± 55	22 ± 16	n.d.
TI Immune + anti-CD40	148,006 ± 72,510	203,081 ± 76,175	54,727 ± 17,381
TD Immune	710,016 ± 131,302	985,402 ± 45,787	270,258 ± 27,546

^a)

NP-specific IgG₁, IgG_2a, and IgG₃ were measured by ELISA as previously described. One of four independent experiments.

^b)

(n.d., not detected).