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. Author manuscript; available in PMC: 2010 Feb 23.
Published in final edited form as: Nat Cell Biol. 2008 Sep;10(9):1039–1050. doi: 10.1038/ncb1763

Figure 7.

Figure 7

Rescue of adhesion maturation in α-actinin-depleted cells by overexpression of MIIA. (a–c) Time-lapse TIRF images of α-actinin-depleted CHO.K1 cells expressing paxillin–mOrange and GFP–actin (a), GFP–MIIA–N93K (b) and GFP–MIIA (c). For convenience, only paxillin is shown. Arrowheads indicate representative maturing adhesions. Scale bars are 5 μm. These panels correspond to Supplementary Information, Movie 11. (d) Quantification of the elongation index of maturing adhesions in the different conditions. Data are mean ± s.e.m., measured from more than 25 adhesions from 5–6 cells per condition; *P = 6 × 10−9, Student’s two-tailed t-test.