Skip to main content
. Author manuscript; available in PMC: 2010 Oct 16.
Published in final edited form as: J Mol Biol. 2009 Aug 13;393(1):176–190. doi: 10.1016/j.jmb.2009.08.012

Figure 8.

Figure 8

A schematic showing residues of the ‘elbow’ region of the IgE-Fc3-4. Hinge residues are shown in blue (P343, S344, P345, R351, K352, K435 and T436). Residues that line the hydrophobic pocket observed in closed-form IgE-Fcs are shown in yellow (L348, F349, W410, I411, R342 and P471). Residues that can form salt bridges are outlined in red and shown connected by dashed red lines (R342 and E472 at the dimer interface side, R440 and E529 on the outer face). Most of the contacts made by AB helix residues are to residues in the C4 domain. Contacts made by helix residues in both open and closed forms are shown with black lines, contacts made only in the open form are shown in blue lines, and the contact made only in the closed form is shown in a solid red line.