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. Author manuscript; available in PMC: 2010 Feb 23.
Published in final edited form as: J Immunol. 2008 Jan 15;180(2):1207–1216. doi: 10.4049/jimmunol.180.2.1207

FIGURE 2.

FIGURE 2

Induction of IL-18 protein expression by H. pylori infection from primary gastric epithelial cells and THP-1 cells. H. pylori were added to exponentially growing cells in 24-well plates at an MOI of 0–500 (THP-1 cells) or at an MOI of 100 (primary gastric epithelial cells) for 20 h (A); H. pylori were added to the exponentially growing THP-1 cells at an MOI of 100 for 0–36 h (B). IL-18 protein levels released from human cells were determined by ELISA. Three independent cocultures were performed and each was measured in duplicate. Data are expressed as mean ± SE. *, p < 0.001 compared with uninfected control; and #, p < 0.01 and ##, p < 0.001 compared with infected samples (MOI of 100) by nonpaired t test.