Table 1.
Comparison of clinical characteristics of diabetic subjects according to the TNF-α-C-857T polymorphism and statin treatment
| All subjects |
Subjects without statin treatment |
Subjects with statin treatment |
||||
|---|---|---|---|---|---|---|
| C/C | C/T,T/T | C/C | C/T,T/T | C/C | C/T,T/T | |
| Sex (male/female) | 116/115 | 44/47 | 77/59 | 29/20 | 39/56 | 15/27 |
| Age (years) | 62.9 ± 10.9 | 62.2 ± 13.6 | 62.3 ± 11.7 | 62.3 ± 15.8 | 63.4 ± 9.6 | 61.9 ± 11.0 |
| Height (cm) | 158.6 ± 8.8 | 156.7 ± 15.4 | 159.3 ± 9.2 | 159.1 ± 8.7 | 157.5 ± 8.4 | 156.3 ± 8.7 |
| Body wt (kg) | 62.5 ± 11.8 | 61.5 ± 12.4 | 61.2 ± 11.6 | 60.9 ± 12.6 | 63.4 ± 13.9 | 62.5 ± 12.4 |
| BMI (kg/m2) | 24.8 ± 4.0 | 24.1 ± 3.5 | 23.8 ± 4.1 | 23.8 ± 3.6 | 25.9 ± 4.2 | 24.8 ± 3.4 |
| Systolic blood pressure (mmHg) | 134.8 ± 19.9 | 134.1 ± 17.7 | 136.2 ± 21.5 | 132.3 ± 18.1 | 134.9 ± 18.1 | 136.8 ± 17.6 |
| Diastolic blood pressure (mmHg) | 78.0 ± 13.3 | 74.9 ± 11.6 | 78.8 ± 13.9 | 73.4 ± 10.6 | 76.1 ± 12.4 | 76.5 ± 12.9 |
| A1C (%) | 7.64 ± 1.73 | 7.39 ± 1.65 | 7.72 ± 1.91 | 7.52 ± 1.70 | 7.59 ± 1.46 | 7.30 ± 1.60 |
| Total cholesterol (mmol/l) | 5.05 ± 0.92 | 5.21 ± 1.02 | 4.95 ± 0.82 | 4.83 ± 0.86 | 5.18 ± 1.05 | 5.68 ± 1.01* |
| Triglycerides (mmol/l) | 1.51 ± 0.95 | 1.52 ± 0.83 | 1.39 ± 0.94 | 1.34 ± 0.88 | 1.51 ± 0.84 | 1.58 ± 0.68 |
| HDL cholesterol (mmol/l) | 1.45 ± 0.45 | 1.48 ± 0.45 | 1.44 ± 0.46 | 1.46 ± 0.49 | 1.46 ± 0.43 | 1.53 ± 0.40 |
| LDL cholesterol (mmol/l) | 2.89 ± 0.75 | 3.14 ± 0.86* | 2.87 ± 0.73 | 2.89 ± 0.76 | 2.90 ± 0.78 | 3.43 ± 0.89† |
Data are means ± SD.
*P < 0.05 (vs. C/C);
†P < 0.0001 (vs. C/C).