Table 2.

Predictors of no improvement, nonresponse, nonpartial remission, and nonfull remission to pharmacotherapy of MDD (n = 352)

	No improvement (R2 = 0.06)*			Nonresponse (R2 = 0.09)			Nonpartial remission (R2 = 0.15)*			Nonfull remission (R2 = 0.10)
	β	OR† (95% CI)‡	P	β	OR† (95% CI)‡	P	β	OR† (95% CI)‡	P	β	OR† (95% CI)‡	P
Sertraline treatment	−0.24	0.79 (0.37–1.69)	0.54	0.91	2.47 (1.39–4.41)	0.002	1.03	2.80 (1.59–4.94)	<0.001	0.26	1.29 (0.77–2.18)	0.33
Higher iBDI	0.02	1.02 (0.98–1.06)	0.32	−0.01	1.00 (0.97–1.02)	0.74	0.05	1.06 (1.03–1.09)	<0.001	0.06	1.06 (1.03–1.09)	<0.001
Family history of depression	−0.25	0.78 (0.40–1.51)	0.46	−0.13	0.88 (0.55–1.40)	0.59	0.02	1.02 (0.64–1.63)	0.93	−0.12	0.89 (0.56–1.40)	0.60
eDC	1.01	2.75 (1.24–6.11)	0.01	0.82	2.27 (1.37–3.76)	0.001	0.71	2.04 (1.25–3.34)	0.005	0.40	1.49 (0.93–2.38)	0.10
Higher baseline A1C	0.04	1.04 (0.90–1.20)	0.61	0.01	1.01 (0.91–1.13)	0.86	−0.03	0.97 (0.87–1.08)	0.55	0.02	1.02 (0.92–1.14)	0.72
Younger age	0.02	1.02 (0.99–1.06)	0.19	0.03	1.03 (1.01–1.05)	0.009	0.02	1.02 (1.00–1.04)	0.06	0.02	1.02 (1.00–1.05)	0.04
Non-Caucasian race	−0.30	0.74 (0.34–1.62)	0.45	0.15	1.16 (0.68–1.97)	0.59	0.05	1.05 (0.61–1.78)	0.87	0.09	1.09 (0.65–1.83)	0.73
Female sex	0.05	1.06 (0.53–2.10)	0.88	0.10	1.11 (0.68–1.80)	0.68	0.11	1.12 (0.69–1.81)	0.65	0.04	1.04 (0.66–1.66)	0.86

*Nagelkerke R² value.

†Coefficient for the constant.

‡OR/exponential β value (95% CI).