Table 1.
Clinical features of subjects with KPDM, ketosis-resistant type 2 diabetes with hyperglycemia (ketosis resistant), and nondiabetic control subjects
| KPDM | Ketosis resistant | Nondiabetic control subjects | |
|---|---|---|---|
| n | 8 | 8 | 9 |
| Age (years) | 39 ± 10 | 48 ± 9 | 40 ± 7 |
| Sex (male/female) (n) | 6/2 | 6/2 | 2/7 |
| Race (African Americans) (%) | 8 (100) | 8 (100) | 9 (100) |
| Newly diagnosed diabetes (%) | 8 (100) | 8 (100) | — |
| Family history of diabetes (%) | 7 (88) | 8 (100) | 8 (89) |
| BMI (kg/m2) | 38 ± 4 | 38 ± 5 | 37 ± 9 |
| Positive GAD antibodies (%) | 0 (0) | 0 (0) | — |
| A1C at presentation (%) | 12.1 ± 3 | 12.8 ± 2 | — |
| Blood glucose at presentation (mg/dl) | 891 ± 282 | 537 ± 140 | 88 ± 9 |
| Bicarbonate (mEq/l) | 14 ± 4 | 23 ± 3 | — |
| pH | 7.19 ± 0.24 | 7.36 ± 0.04 | — |
| Anion gap (mEq/l) | 23 ± 7 | 14 ± 7 | — |
| Time to insulin discontinuation (remission) (weeks) | 11.0 ± 8.0 | 9.6 ± 2.2 | — |
| A1C at remission (%) | 5.7 ± 0.4 | 6.3 ± 1.1 | — |
| Blood glucose at remission (mg/dl) | 94 ± 14 | 109 ± 20 | — |
Data are means ± SD, unless otherwise indicated.