Table 1.
Threshold values for diagnosis of GDM or overt diabetes in pregnancy
| To diagnose GDM and cumulative proportion of HAPO cohort equaling or exceeding those thresholds | |||
|---|---|---|---|
| Glucose measure | Glucose concentration threshold* |
Above threshold (%) |
|
| mmol/l | mg/dl | Cumulative | |
| FPG | 5.1 | 92 | 8.3 |
| 1-h plasma glucose | 10.0 | 180 | 14.0 |
| 2-h plasma glucose | 8.5 | 153 | 16.1† |
| To diagnose overt diabetes in pregnancy | |
|---|---|
| Measure of glycemia | Consensus threshold |
| FPG‡ | ≥7.0 mmol/l (126 mg/dl) |
| A1C‡ | ≥6.5% (DCCT/UKPDS standardized) |
| Random plasma glucose | ≥11.1 mmol/l (200 mg/dl) + confirmation§ |
*One or more of these values from a 75-g OGTT must be equaled or exceeded for the diagnosis of GDM.
†In addition, 1.7% of participants in the initial cohort were unblinded because of FPG >5.8 mmol/l (105 mg/dl) or 2-h OGTT values >11.1 mmol/l (200 mg/dl), bringing the total to 17.8%.
‡One of these must be met to identify the patient as having overt diabetes in pregnancy.
§If a random plasma glucose is the initial measure, the tentative diagnosis of overt diabetes in pregnancy should be confirmed by FPG or A1C using a DCCT/UKPDS-standardized assay.