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. 2010 Feb 24;5(2):e9386. doi: 10.1371/journal.pone.0009386

Figure 3. Probablility of clinical onset in CR vs. AL G93A mice.

Figure 3

Probability of clinical onset in 23 ad libitum (AL: •, 16 females; ▪, 7 males) and 31 calorie restricted (CR, 60% of ad libitum: ○, 21 females; □, 10 males) G93A mice. The rate of attaining clinical onset (i.e., the hazard ratio) in the CR mice was 2-fold higher (95% CI: 1.4, 4.7) than the AL mice. CR females had a 2-fold (95% CI: 1.2, 5.3) higher rate of attaining clinical onset as compared with AL females (P = 0.016). There was no sex difference in the rate of attaining clinical onset.