Table 1. Genes with changed transcript levels after fasting in wild type (WT) and Snord116del (Del) hypothalami of postnatal day 5 mice.
Gene Symbol | Gene Name | Accession number Mouse | Change in WT | Change in Del | Li 2002* | |||
Fold | P value | Fold | P value | Rat Gene ID | Result | |||
Increased | ||||||||
Nanos2 | Nanos homolog 2 (Drosophila) | NM_194064.2 | 2.03±0.17 | <0.0002 | 1.88±0.07 | <0.0001 | 365213 | NA |
Pdk4 | Pyruvate dehydrogenase kinase, isoenzyme 4 | NM_013743.2 | 1.55±0.19 | <0.02 | 1.53±0.12 | <0.05 | 89813 | N |
Decreased | ||||||||
Brms1l | Breast cancer metastasis-suppressor 1-like | NM_027867.2 | 0.74±0.04 | <0.005 | 0.68±0.02 | <0.01 | 299053 | N |
Mett10d | Methyltransferase 10 domain containing | NM_026197.1 | 0.62±0.04 | <0.00001 | 0.66±0.04 | <0.0005 | 360568 | N |
Ndp | Norrie disease homolog (Ndp) | NM_010883.2 | 0.62±0.08 | <0.0005 | 0.62±0.11 | <0.01 | 363443 | NA |
Pgpep1 | Pyroglutamyl-peptidase I | NM_023217.2 | 0.61±0.11 | <0.02 | 0.46±0.07 | <0.0001 | 290648 | N |
Snx1 | Sorting nexin 1 | NM_019727.1 | 0.60±0.05 | <0.0001 | 0.60±0.06 | <0.001 | 84471 | N |
*Data reported for adult rats [9]. NA, gene not present on rat array, N, expression unchanged upon fasting.