Table 2.
Urine NGAL, ng/ml, |
P | ||
---|---|---|---|
No AKI | AKI-Positive | ||
eGFR 0 to 30 ml/min (n = 21) | |||
n | 12 | 9 | |
Preoperative | 20 (11 to 379) | 32 (10 to 76) | 0.91 |
Immediately after CPB | 300 (146 to 1349) | 295 (87 to 933) | 0.62 |
3 h after CPB | 339 (15 to 904) | 329 (112 to 1638) | 0.68 |
18 h after CPB | 788 (96 to 3120) | 260 (98 to 2607) | 0.63 |
24 h after CPB | 1380 (151 to 5144) | 755 (152 to 813) | 0.37 |
eGFR 30 to 60 ml/min (n = 101) | |||
n | 81 | 20 | |
Preoperative | 10 (3 to 44) | 7 (3 to 83) | 0.96 |
Immediately after CPB | 731 (39 to 1951) | 630 (130 to 2216) | 0.64 |
3 h after CPB | 463 (16 to 1385) | 407 (59 to 1546) | 0.64 |
18 h after CPB | 44 (14 to 800) | 88 (32 to 608) | 0.48 |
24 h after CPB | 80 (21 to 958) | 291 (28 to 642) | 0.92 |
eGFR 60 to 90 ml/min (n = 142) | |||
n | 107 | 35 | |
Preoperative | 7 (3 to 21) | 8 (3 to 26) | 0.96 |
Immediately after CPB | 549 (7 to 1993) | 1740 (157 to 4399) | 0.01 |
3 h after CPB | 106 (4 to 830) | 1335 (14 to 2714) | 0.001 |
18 h after CPB | 37 (11 to 195) | 53 (23 to 483) | 0.13 |
24 h after CPB | 44 (14 to 318) | 46 (25 to 464) | 0.40 |
eGFR 90 to 120 ml/min (n = 109) | |||
n | 96 | 13 | |
Preoperative | 5 (2 to 10) | 22 (6 to 38) | 0.03 |
Immediately after CPB | 43 (5 to 1472) | 1354 (34 to 2674) | 0.06 |
3 h after CPB | 17 (3 to 405) | 256 (29 to 3003) | 0.049 |
18 h after CPB | 15 (7 to 40) | 148 (39 to 313) | 0.002 |
24 h after CPB | 18 (10 to 33) | 283 (72 to 866) | 0.0001 |
eGFR >120 ml/min (n = 53) | |||
n | 45 | 8 | |
Preoperative | 5 (2 to 12) | 5 (2 to 9) | 0.82 |
Immediately after CPB | 1047 (18 to 2795) | 3 (0 to 1922) | 0.01 |
3 h after CPB | 88 (12 to 2195) | 1 (1 to 6) | 0.03 |
18 h after CPB | 17 (6 to 55) | 9 (3 to 16) | 0.08 |
24 h after CPB | 19 (8 to 99) | 8 (4 to 15) | 0.05 |
Values are given as median, with interquartile range in parentheses. Comparisons are stratified by baseline renal function determined by eGFR (calculated by Cockroft-Gault equation). Comparisons are made using Mann-Whitney U test.