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. 2010 Feb;5(2):211–219. doi: 10.2215/CJN.04240609

Table 2.

Urinary NGAL levels at various time points preoperatively and postoperatively, comparing patients who developed AKI with those who did not

Urine NGAL, ng/ml,
P
No AKI AKI-Positive
eGFR 0 to 30 ml/min (n = 21)
    n 12 9
    Preoperative 20 (11 to 379) 32 (10 to 76) 0.91
    Immediately after CPB 300 (146 to 1349) 295 (87 to 933) 0.62
    3 h after CPB 339 (15 to 904) 329 (112 to 1638) 0.68
    18 h after CPB 788 (96 to 3120) 260 (98 to 2607) 0.63
    24 h after CPB 1380 (151 to 5144) 755 (152 to 813) 0.37
eGFR 30 to 60 ml/min (n = 101)
    n 81 20
    Preoperative 10 (3 to 44) 7 (3 to 83) 0.96
    Immediately after CPB 731 (39 to 1951) 630 (130 to 2216) 0.64
    3 h after CPB 463 (16 to 1385) 407 (59 to 1546) 0.64
    18 h after CPB 44 (14 to 800) 88 (32 to 608) 0.48
    24 h after CPB 80 (21 to 958) 291 (28 to 642) 0.92
eGFR 60 to 90 ml/min (n = 142)
    n 107 35
    Preoperative 7 (3 to 21) 8 (3 to 26) 0.96
    Immediately after CPB 549 (7 to 1993) 1740 (157 to 4399) 0.01
    3 h after CPB 106 (4 to 830) 1335 (14 to 2714) 0.001
    18 h after CPB 37 (11 to 195) 53 (23 to 483) 0.13
    24 h after CPB 44 (14 to 318) 46 (25 to 464) 0.40
eGFR 90 to 120 ml/min (n = 109)
    n 96 13
    Preoperative 5 (2 to 10) 22 (6 to 38) 0.03
    Immediately after CPB 43 (5 to 1472) 1354 (34 to 2674) 0.06
    3 h after CPB 17 (3 to 405) 256 (29 to 3003) 0.049
    18 h after CPB 15 (7 to 40) 148 (39 to 313) 0.002
    24 h after CPB 18 (10 to 33) 283 (72 to 866) 0.0001
eGFR >120 ml/min (n = 53)
    n 45 8
    Preoperative 5 (2 to 12) 5 (2 to 9) 0.82
    Immediately after CPB 1047 (18 to 2795) 3 (0 to 1922) 0.01
    3 h after CPB 88 (12 to 2195) 1 (1 to 6) 0.03
    18 h after CPB 17 (6 to 55) 9 (3 to 16) 0.08
    24 h after CPB 19 (8 to 99) 8 (4 to 15) 0.05

Values are given as median, with interquartile range in parentheses. Comparisons are stratified by baseline renal function determined by eGFR (calculated by Cockroft-Gault equation). Comparisons are made using Mann-Whitney U test.