Figure 6. Disorganization of interneuronal localization in MAM brains.

A: and C: GABA-positive (A) and Calbindin-positive (C) interneurons were well-organized in the E19 control neocortex, localized especially within the MZ and the intermediate zone. A few labeled cells were also seen in the CP. B and D: In the MAM-treated brain, both GABA-positive (B) and Calbindin-positive (D) cells were scattered throughout the neocortex and there was no distinct localization as was seen in the control brain. Scale bar: A,B = 80mm; C,D = 50mm