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. Author manuscript; available in PMC: 2011 Mar 5.
Published in final edited form as: FEBS Lett. 2010 Jan 30;584(5):1006–1010. doi: 10.1016/j.febslet.2010.01.049

Fig. 4. PTTG1 is upregulated with KLF6 knockdown.

Fig. 4

HepG2 cells were transfected with siKLF6 or siControl and RNA and protein collected after 24hrs. (A) QRTPCR on cDNA showed 57% decrease in KLF6 mRNA, with a corresponding 3.7-fold increase in PTTG1. (B) Protein extracts were submitted to Western Blot analysis and approximately a 50% decrease in KLF6 protein levels resulted in approximately 2-fold overexpression of PTTG1. The data presented in (B) is representative of at least 3 independent experiments.