Table 1.
Summary of physicochemical properties of isomers of CLA-PC compared to LA-PC.
| Property | Control (LA-PC) | t10 c12 CLA-PC | t9 t11 CLA-PC | c9 t11 CLA-PC | c9 c11 CLA-PC |
|---|---|---|---|---|---|
| Area at 20 mN/m (Å2/mole) | 73.8 | 58.2 | 53.2 | 58.8 | 76.2 |
| Area condensation with 10% chol. at 20 mN/m | 3% | 7% | 7% | 2% | −1% |
| Chol. binding (% of Cont) | 100 | 118.5 | 210.3 | 98.6 | 84.5 |
| Tm of DPPC (+25% test PC) | 36.2 °C | 36.5 °C | 37.5 °C | 34.7 °C | 35.4 °C |
| Cooperative unit1 (DPPC +25% test PC) | 23.9 | 24.1 | 48.6 | 19.2 | 17.9 |
| DPH-PC anisotropy (37 °C) (% of Cont.) | 100 | 106.1 | 114.3 | 101.7 | 154.9 |
| Permeability (% of Cont.) | 100 | 89.3 | 8.5 | 140.6 | 40.0 |
| Oxidizability (% of Cont.) | 100 | 336 | 312 | 339 | 184 |
| LCAT activity (% of Cont.) | 100 | 230 | 14 | 195 | 81 |
1
Cooperative unit (C.U) was obtained by dividing the van’t Hoff enthalpy (ΔHVH) with the calorimetric enthalpy (ΔH). The C.U value for pure DPPC was 539.