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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2009 Oct 29;21(3):323–337. doi: 10.1016/j.jasms.2009.10.013

Figure 5.

Figure 5

A schematic representation of the JAK/STAT pathway activation by IFN initiated by its binding with the receptors IFNAR1 and IFNAR2 (A), adapted from (45); and the proposed sequence of events leading to the assembly of the ternary complex IFNAR2/IFN/IFNAR1 (B).