TABLE 4:
Case fatality of early-onset neonatal group B streptococcal (GBS) disease cases in the presence or absence of clinical risk factors
| Clinical risk factor | Number (%) who died with risk factor* | Number (%) who died without risk factor* | P |
|---|---|---|---|
| Intrapartum fever >38°C | 3/13 (23.1) | 11/58 (19.0) | 0.71 |
| Chorioamnionitis | 4/10 (40.0) | 10/53 (18.9) | 0.21 |
| Intrapartum antibiotics | 3/14 (21.4)† | 11/48 (22.4) | 0.94 |
| Prolonged rupture of membranes | |||
| ≥12 h | 5/30 (16.7) | 8/37 (21.6) | 0.76 |
| ≥18 h | 3/17 (17.6) | 10/50 (20.0) | 1.00 |
| Gestational age <37 weeks | 10/31 (32.3) | 4/43 (9.3) | 0.02 |
| Birth weight <2500 g | 7/23 (30.4) | 8/52 (15.4) | 0.21 |
| Hours after birth to presentation of infection | |||
| <24 h | 11/54 (20.4) | 5/16 (31.3) | 0.50 |
| <48 h | 14/66 (21.2) | 0/4 (0) | 0.58 |
| Inborn | 10/40 (25.0) | 3/26 (11.5) | 0.18 |
*
Numerator is number who died, denominator is number with clinical feature present or absent. Denominators do not always total 78 because of missing data;
†
All three who died received only one dose of antibiotics