Skip to main content
. 2009 Nov 30;42(2):105–115. doi: 10.3858/emm.2010.42.2.012

Figure 6.

Figure 6

Whole cell lysates of PC-12 cells treated with (A) 1.2 mM phenylpyruvic acid were used for detection of phosphorylated ERK1/2 and total ERK1/2. Western blot analysis was performed to detect transthyretin expression levels in PC-12 cells treated with (B) 1.2 mM phenylpyruvic acid after preincubation with ERK inhibitor II. The cells were exposed to phenylpyruvic acid for 7 days. Transthyretin levels were normalized to GAPDH levels. Values are expressed as the mean ± SD (n = 3-4). *P < 0.05 vs DMSO-treated controls using Student's t-test.