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. Author manuscript; available in PMC: 2010 Feb 24.
Published in final edited form as: Thromb Haemost. 2009 May;101(5):878–885.

Table 3.

Factors Associated with Recurrent VTE in Patients with Venous Thromboembolism

Recurrent VTE Hazard ratio (95% CI)
(n=325)
Demographic Characteristics
Age
 <65 1.0
 65-74 0.79 (0.57, 1.10)
 75-84 0.68 (0.49, 0.93)
 ≥85 0.57 (0.37, 0.88)
Recent (< 3 mo) medical conditions (%)
 Malignancy* 1.38 (1.01-1.89)
 Malignancy** 0.76 (0.40, 1.42)
Other medical history (%)
 Prior VTE* 1.06 (0.75, 1.50)
 Prior VTE** 2.50 (1.48, 4.23)
 Cerebrovascular disease* 1.70 (1.17, 2.48)
 Cerebrovascular disease** 0.95 (0.41, 2.23)
Complications
 Bleeding 2.18 (1.54, 3.09)

Unless otherwise specified, hazards ratios are for recurrent VTE occurring anytime following incident event. As malignancy, prior VTE, and cerebrovascular disease did not meet proportional hazards assumptions, hazard ratios are provided for recurrent VTE occurring < or > 400 days following incident VTE.

*

HR associated with development of VTE < 400 days from incident event

**

Hazards ration associated with development of VTE > 400 days from incident event.