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Type of somatic TP53 mutations in human cancers. (A) Pie charts showing the proportion of the different types of TP53 somatic mutations found in all human cancers. (B) Histogram displaying the position of somatic point mutations in the coding sequence of the TP53 gene. Data from the IARC TP53 Database (R13, November 2008)(Petitjean et al. 2007b).
