Figure 2.

Effect sizes of BOLD signal intensity changes in response to stressful stimuli in men, women during early follicular, and women during late follicular/midcycle. This is a graphic representation of effect sizes in signal intensity changes (data reported in Table 3, columns 6, 7; see table for relevant statistics) for our hypothesized regions of interest in the stress response circuitry. ESs = SDs calculated as follows: differences between negative versus neutral signal intensity changes in men versus EF women and men versus LF/MC women; differences are divided by SD of signal intensity value of the whole sample. The graph illustrates the differences between men (in blue) and women during early follicular (in red) and women during midcycle (in pink) phase of the menstrual cycle. The abbreviations represent the following regions of interest (L, left hemisphere; R, right hemisphere): medPFC, medial prefrontal cortex; HIPPO, hippocampus.