Figure 5. Transplantation of aP2-Dgat1 BM is sufficient to protect against impaired glucose metabolism in mice chronically fed a high-fat diet.

Growth curves (A) and liver and muscle TG content (B) of transplanted mice fed a high-fat diet for 20 weeks showing no differences between mice receiving WT→WT and Tg→WT mice (n = 7–13 per group). (C) Enhanced glucose (top, GTT) and insulin (bottom, ITT) tolerance in Tg→WT mice fed a high-fat diet for 16 weeks (*P < 0.05).