Table 3.

Comparison of the potency of glyceryl trinitrate (–log EC₅₀) against U46619-induced contractions following exposure to 30 µM glyceryl trinitrate (GTN) with or without quercetin or quercetin metabolites (n= 8)

Control	30 µM GTN 90 min	30 µM GTN 90 min 10 µM Quercetin
7.13 ± 0.09	5.58 ± 0.07	6.59 ± 0.22*
Control	30 µM GTN 90 min	30 µM GTN 90 min 10 µM Quercetin glucuronide
6.81 ± 0.13	6.09 ± 0.09	6.13 ± 0.12
Control	30 µM GTN 90 min	30 µM GTN 90 min 10 µM Quercetin sulphate
6.83 ± 11	5.92 ± 0.15	6.57 ± 0.15*

^*Significant difference (P < 0.05, paired Student's t-test) in potency compared to tissue exposed to 30 µM glyceryl trinitrate alone.