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. 2009 Dec 24;159(3):650–658. doi: 10.1111/j.1476-5381.2009.00557.x

Figure 3.

Figure 3

TRAM-34 mimics the effects of 17β-oestradiol (E2) on progesterone receptor (PR) and oestrogen receptor (ER)-α mRNA expression. (A) and (B) Normalized mean PR/hypoxanthine phosphoribosyltransferase (HPRT) or ER-α/HPRT ratios from quantitative RT-PCR ± standard error of the mean, from four separate trials. MCF-7 cells were treated for 24 h with E2 (1 nM), TRAM-34 (TRAM, 10 µM), ICI182,780 (ICI, 1 nM) and clotrimazole (10 µM). *P < 0.05 when compared with controls, †P < 0.05 and N.S., not statistically significant between two indicated treatments.