Table 1.
Baseline characteristics of the Atherosclerosis Risk in Community (ARIC) cohort
| White (N=10 453) | African American (N=3703) | ||
|---|---|---|---|
| Characteristic | Mean (s.e.m.) | Mean (s.e.m.) | *P-value |
| Age (years) | 54.4 (0.05) | 53.6 (0.09) | <0.001 |
| Body mass index (kg m−2) | 27.0 (0.05) | 29.6 (0.01) | <0.001 |
| Total cholesterol (mg per 100 ml) | 215.0 (0.4) | 215.1 (0.72) | 0.9 |
| Total calories (kcal per day) | 1639.0 (5.7) | 1586.1 (9.8) | 0.001 |
| Total fat (%kcal) | 33.1 (0.06) | 32.2 (0.10) | <0.001 |
| Monounsaturated fat (%kcal) | 12.7 (0.04) | 12.6 (0.03) | 0.5 |
| Polyunsaturated fat (%kcal) | 5.1 (0.01) | 4.8 (0.02) | <0.001 |
| Saturated fat (%kcal) | 12.2 (0.03) | 11.5 (0.04) | <0.001 |
| Physical activity (Baeke score) | 7.1 (0.1) | 6.5 (0.02) | <0.001 |
| Systolic blood pressure (mm Hg) | 118.6 (0.2) | 129 (0.3) | <0.001 |
| Diastolic blood pressure (mmHg) | 71.5 (0.1) | 79.8 (0.2) | <0.001 |
| Sodium (mg per day) | 1518.0 (5.9) | 1364.0 (9.2) | <0.001 |
| N (%) | N (%) | ||
| Hypertension | 3116 (27.4) | 2339 (56.0) | <0.001 |
| Diabetes | 1043 (9.1) | 817 (20.0) | <0.001 |
| Current smoker | 2836 (24.8) | 1254 (29.9) | <0.001 |
| NOS3 genotype | |||
| GG | 4966 (46.6) | 2986 (78.1) | <0.001 |
| GT | 4620 (43.3) | 782 (20.5) | <0.001 |
| TT | 1076 (10.1) | 54 (1.4) | <0.001 |
*
P-value comparing whites and African Americans.