Table 3.
Weekly Symptomatic Status and Changes in Mood Polarity by Bipolar Subtype
| All Sample (n=413) | Bipolar-I (n=244) | Bipolar-II (n=28) | Bipolar-NOS (n=141) | Analyses | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | df | χ2 | p | |
| Asymptomatic (%) | 41.2 | 31.6 | 44.0a | 30.6 | 45.0a,b | 33.6 | 35.6b | 32.4 | 2 | 8.08 | 0.02 |
| Syndromal (%) | 16.6 | 21.9 | 17.8a | 19.8 | 24.6a | 28.0 | 12.8b | 23.3 | 2 | 31.74 | 0.001 |
| Mania | 0.9 | 4.1 | 1.6a | 5.3 | 0.0b | 0.0 | 0.0b | 0.0 | 2 | 61.49 | 0.001 |
| Hypomania | 1.8 | 6.1 | 2.7 | a 7.7 | 1.4a | 2.7 | 0.3b | 1.5 | 2 | 30.22 | 0.001 |
| Mixed/Cycling | 7.9 | 16.1 | 8.1a | 13.3 | 10.8a,b | 22.1 | 7.0b | 19.0 | 2 | 15.40 | 0.001 |
| MDD | 6.0 | 13.1 | 5.5a | 11.1 | 12.4b | 19.4 | 5.5a | 14.3 | 2 | 13.47 | 0.001 |
| Subsyndromal (%) | 41.8 | 28.8 | 38.2a | 25.4 | 30.4a | 26.0 | 50.2b | 32.8 | 2 | 16.24 | 0.001 |
| Mania | 14.1 | 18.9 | 14.1a | 17.1 | 7.0b | 10.9 | 15.6a,b | 22.5 | 2 | 6.14 | 0.05 |
| Mixed | 15.4 | 22.2 | 13.2 | 18.6 | 8.9 | 16.5 | 20.6 | 27.4 | 2 | 4.78 | 0.09 |
| Depression | 12.2 | 16.9 | 10.9 | 14.2 | 14.5 | 21.2 | 14.1 | 20.0 | 2 | 0.41 | 0.8 |
| Psychosis (delusions and/or hallucinations) | 3.1 | 12.9 | 3.4a | 12.1 | 5.5a,b | 20.5 | 2.3b | 12.3 | 2 | 11.99 | 0.002 |
|
Changes in Mood Polarity, times per year † | |||||||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||||
| 12.1 | 15.0 | 11.0 | 13.8 | 10.3 | 16.3 | 14.3 | 16.7 | 2 | 2.46 | 0.3 | |
| N | % | N | % | N | % | N | % | ||||
| ≤1 | 129 | 31.2 | 72 | 29.5 | 10 | 35.7 | 47 | 33.3 | 2 | 0.89 | 0.6 |
| >5 | 211 | 51.1 | 123 | 50.4 | 10 | 35.7 | 78 | 55.3 | 2 | 3.70 | 0.2 |
| >10 | 160 | 38.7 | 87 | 35.7a | 7 | 25.0a | 66 | 46.8b | 2 | 7.07 | 0.03 |
| >20 | 98 | 23.7 | 51 | 20.9 | 5 | 17.9 | 42 | 29.8 | 2 | 4.47 | 0.1 |
Different superscripts indicate significant pair-wise differences at p ≤ 0.05
†
Indicates switch between depression (psychiatric Status Rating, ≥3) and mania/hypomania (Psychiatric Status Rating, ≥3) or vice versa with or without intervening weeks at the asymptomatic status.