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. 2003 Dec;15(12):2826–2842. doi: 10.1105/tpc.016246

Figure 1.

Figure 1.

Myo5 Is a Class-V Myosin.

(A) A dendrogram of myosins created by the distance-based minimum-evolution method, based on 500 replicates. Note that U. maydis contains one myosin of class V, I, and II. Bootstrap values are given, and branching points and the scale bar denote substitutions per site. Sc, Saccharomyces cerevisiae; Um, Ustilago maydis; Sp, Schizosaccharomyces pombe; Mm, Mus musculus; Gg, Gallus gallus; Dd, Dictyostelium discoideum; An, Aspergillus nidulans.

(B) Dot plot comparison of Myo5 and Myo2p from S. cerevisiae. Note that both motors share significant sequence identity over the entire length.

(C) Comparison of the domain structures of Myo5 and Myo2p from S. cerevisiae, Myo52/Myo4 of S. pombe, and mouse Myo5A. Myo5 contains all predicted domains that are typical for class-V myosins. AA, amino acids.