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. Author manuscript; available in PMC: 2010 Feb 24.
Published in final edited form as: Free Radic Biol Med. 2008 Nov 1;46(3):376–386. doi: 10.1016/j.freeradbiomed.2008.10.026

Fig. 6. Nrf2 binds to Srx1 promoter in vivo.

Fig. 6

(A) CHIP assay was performed with A549 cells stably expressing Nrf2shRNA and the control cells expressing luciferase shRNA. PCR reactions were performed to amplify the Srx1 regulatory region encompassing ARE1. (B) Increased recruitment of Nrf2 to ARE1 consensus sequence in the Srx1 promoter in response to TBHQ treatment.