Table 3.
Variable region diversity and light chain usage among mammals.
| Species | VH (Fa) | DH | JH | Vλ (Fa) | Jλ | Cλ | % Use | Vκ (Fa) | Jκ | Cκ | % Use |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 87 (7) | 28 | 9 | 70 (7) | 7 | 7b | 40 | 66 (7) | 5 | 1 | 60 |
| Mouse | >100 (14) | 11 | 4 | 3 (3) | 4 | 4b | 5 | 140 (4) | 4 | 1 | 95 |
| Rat | >100 (11) | 9 | 5 | 15 (4) | 1 | 1 | 9 | 18 (?) | 6 | 9 | |
| Rabbit | >100 (1) | 12 | 6 | ? (?) | 2 | 2 | 10 | >36 | 5 | 2 | 90 |
| Swine | <25 (1) | 3 | 1 | ? (4) | 3? | 3? | 50 | 60 (2) | 5 | 1 | 50 |
| Horse | 10 (2) | 9 | 9 | 25 (3) | 4 | 4 | 93 | 20 (?) | 5 | 1 | 7 |
| Bovine | 15 (2?) | 9 | 2(1) | 20 (?) | 2 | 4 | 98 | ? (?) | 9 | 1 | 2 |
| Sheep | 10 (1) | ? | ? | >100 (?) | 1 | >1 | 98 | 10 (4) | 3? | 1 | 2 |
| Camelid | 42 VHH (1) | ? (?) | ? | 2 | ? | ? (?) | ? | 1 | ? | ||
| 50 VH (1) | 10 | 6 | |||||||||
| Opossum | 12 | ? | ? | 30 (3) | 6 | 6 | ? | 35 (4) | 2+ | 1 | ? |
| Platypus | 25 (1) | >5 | 7 | 15–25 (2) | 6 (3) | 4 | 90 | ? (4+) | ? | ? | 10 |
a
Number of families (F) of variable region genes.
b
Jλ–Cλ occurs as duplicons.