Table 2.
Multivariate Cox regression analysis for prediction of disease progression
| Variable | Progression | |
|---|---|---|
| HR (95% CI) | P-value | |
| Stage (Ta vs. T1) | 0.258 (0.032 - 2.083) | 0.204 |
| Grade (low vs. high) | 2.257 (0.445 - 11.449) | 0.326 |
| Number of tumors | ||
| Single | Reference | - |
| 2 to 7 | 1.684 (0.314 - 9.027) | 0.543 |
| >8 | 4.544 (0.624 - 32.141) | 0.129 |
| Size (> 3 cm vs. ≤ 3 cm) | 1.933 (0.397 - 9.411) | 0.414 |
| Intravesical therapy (Yes vs. No) | 2.141 (0.391 - 11.715) | 0.38 |
| S100A8-correlated gene signature (HSC vs. LSC) | 15.225 (1.736 - 133.52) | 0.014 |
Abbreviations: HR, hazards ratio; CI, confidence interval