Table 4.
Genes differentially expressed in individual OA meniscal cells compared to normal meniscal cells.
| Gene Name |
Gene ID | OA1 | OA1 | OA3 | OA4 | OA5 | Description |
|---|---|---|---|---|---|---|---|
| BST1 | NM_004334 | 3.9 | 3.4 | 3.3 | 1.6 | 2.2 | bone marrow stromal cell antigen 1 |
| FGF9 | NM_002010 | 3.7 | 2.4 | 3.7 | 2.5 | 2.9 | Fibroblast growth factor 9 |
| ACAN | NM_013227 | 2.4 | 1.6 | 1.6 | 0.0 | 1.6 | Aggrecan |
| COL11A1 | J04177 | 0.0 | 11.5 | 5.8 | 2.2 | 3.6 | Collagen, type XI, alpha 1 |
| ANKH | AL833238 | 0.0 | 1.8 | 1.7 | 1.5 | 1.8 | Ankylosis, progressive homolog (mouse) |
| MGP | NM_000900 | 11.8 | 4.7 | 21.6 | 0.0 | 17.6 | Matrix Gla protein |
| TUFT1 | NM_020127 | 2.8 | 2.7 | 1.9 | 0.0 | 0.0 | Tuftelin 1 |
| TFIP11 | NM_012143 | 2.2 | 1.6 | 0.0 | 0.0 | 0.0 | Tuftelin interacting protein 11 |
| IL20RB | AL578102 | 2.3 | 2.7 | 0.0 | 2.6 | 7.8 | Interleukin 20 receptor beta |
| IL26 | NM_018402 | 1.7 | 1.6 | 1.6 | 0.0 | 3.0 | Interleukin 26 |
| COL4A5 | AW052179 | -3.1 | -3.0 | -3.1 | -3.0 | -3.1 | Collagen, type IV, alpha 5 (Alport syndrome) |
| MMP9 | NM_004994 | -2.2 | -2.1 | -2.1 | 0.0 | -2.2 | Matrix metallopeptidase 9 |
| MMP10 | NM_002425 | -2.7 | -2.6 | -2.7 | -1.5 | -2.6 | Matrix metallopeptidase 10 |
| MMP12 | NM_002426 | -2.1 | -2.0 | -2.1 | 0.0 | -2.1 | Matrix metallopeptidase 12 |
| FZD10 | NM_007197 | -1.6 | -1.5 | -1.6 | -1.5 | -1.5 | Frizzled homolog 10 (Drosophila) |
| CYTL1 | NM_018659 | -2.6 | -2.6 | -2.6 | -2.6 | -2.5 | Cytokine-like 1 |
| CHODL | NM_024944 | -2.6 | -2.6 | -2.6 | -2.6 | Chondrolectin | |
*Positive number indicates elevated expression (fold) in OA meniscal cells compared to normal meniscal cells. Negative number indicates decreased expression (fold) in OA meniscal cells compared to normal meniscal cells. 0.0 indicates there was no differential gene expression being detected.