Figure 2. The aminoglycoside resistance gene cluster.
The two genes smi_1689 and smi_1720 flanking the cluster are conserved in S. pneumoniae and S. mitis. Red: genes implicated in antibiotic resistance as indicated above the genes; black: IS and recombinases; hatched: S. mitis B6 specific hypothetical genes. Thick lines below mark regions with homology to genes in other species as indicated. The fat arrows left and right mark repeat sequences.