Table 3.

Univariate analyses of predictive factors for survival of patients with stage II adenocarcinoma of the pancreas after PD or PPPD, with or without vascular resection

Parameters	Median (mo)	95% CI of median	3-yr survival (%)	P value
Age (yr)				0.852
≤ 70 (n = 62)	11.51	7.78-15.25	12.0
> 70 (n = 23)	9.40	9.15-9.65	16.3
Sex				0.191
Male (n = 55)	9.76	7.61-11.91	9.6
Female (n = 30)	14.01	3.20-24.82	19.4
Albumin (g/dL)				0.107
≤ 3.5 (n = 21)	7.40	3.86-10.94	12.7
> 3.5 (n = 47)	11.67	5.96-17.38	12.8
Total bilirubin (mg/dL)				0.008
≤ 2 (n = 19)	17.39	15.23-19.55	30.7
> 2 (n = 65)	9.40	7.66-11.14	3.5
Serum CA 19-9 (U/L)				0.167
≤ 37 (n = 16)	16.11	1.47-30.75	25.0
> 37 (n = 54)	11.51	8.17-14.85	12.3
Serum CEA (ng/mL)				0.455
≤ 5 (n = 40)	16.08	10.78-21.38	13.4
> 5 (n = 24)	7.82	5.18-10.46.	16.7
Blood transfusion				0.491
Yes (n = 47)	10.88	7.17-14.59	14.9
No (n = 38)	9.24	5.59-12.89	9.8
Tumor size (cm)
≤ 3 (n = 43)	13.97	10.77-17.18	13.3	0.508
> 3 (n = 41)	9.27	8.82-9.72	12.5
Nodal metastases				0.557
Yes (n = 71)	9.76	7.69-11.83	13.6
No (n = 14)	12.16	0.00-28.36	8.3
Pre-op biliary drainage				0.262
Yes (n = 49)	9.24	7.80-10.68	12.0
No (n = 36)	13.97	9.44-18.50	14.3
PV/SMV resection				0.994
Yes (n = 12)	9.27	0.00-19.54	16.7
No (n = 73)	10.36	7.87-12.86	12.2
Resection margin1				0.071
Negative (n = 58)	11.51	6.46-16.56	16.1
Positive (n = 27)	9.27	7.46-11.08	5.1
Differentiation				0.016
Well (n = 25)	20.98	9.02-32.94	24.0
Moderately (n = 45)	8.81	7.81-9.81	8.8
Poorly (n = 15)	10.49	7.01-13.97	6.7
Adjuvant chemotherapy				0.008
Yes (n = 53)	12.99	10.44-12.74	18.8
No (n = 32)	7.96	5.74-10.19	3.2

Two cases of mortality were not included in survival analysis.

¹Resection margin was negative in all 12 patients who underwent vascular resection.