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. Author manuscript; available in PMC: 2011 Mar 15.
Published in final edited form as: Virology. 2009 Dec 30;398(2):201–207. doi: 10.1016/j.virol.2009.11.046

Figure 6.

Figure 6

Mean frequency of amino acid mutations and net charge changes within the V4 loop from brain sequences of morphine-dependent and control macaques infected with SIV/17E-Fr, SHIVKU-1B and SHIV89.6P. Panel A, The mean frequency of amino acid mutations was calculated as the total number of mutations in monkey divided by the number of clones. Represented are the averages of mutations per group. Panel B, The net charge of the V4 loop was calculated by subtracting the number of negatively charged amino acids from the number of positively charged amino acids. Represented are the averages of the net charge per group. Error bars indicate standard deviation.