TABLE 3.
Anthropometric and metabolic parameters at follow-up
Nonprogressors (n = 213) | Progressors (n = 115) | P§ | |
---|---|---|---|
Follow-up (years) | 3.2 (2.8) | 2.2 (3.3) | <0.0001 |
Age (years) | 14.7 (9.6)* | 12.0 (5.7)* | <0.0001 |
Height (m) | 1.63 (0.25)* | 1.52 (0.30)* | 0.0007 |
Weight (kg) | 57 (33)* | 47 (31)* | 0.0035 |
BMI (kg/m2) | 21.1 (6.0)* | 19.6 (6.1)* | <0.05 |
Fasting glucose (mmol/l) | 4.89 (0.65)* | 5.75 (1.22)* | <0.0001 |
2-h glucose (mmol/l) | 6.27 (2.25)* | 13.05 (6.52)* | <0.0001 |
Glucose tolerance (NGT/IGT) (%) | 81/19* | — | <0.0001 |
Fasting insulin secretion (pmol/min per m2) | 65 (33)* | 65 (44)* | ns |
Insulin output (nmol/m2) | 31 (14)* | 21 (15)* | <0.0001 |
Glucose sensitivity (pmol/min per m2 per mmol/l) | 72 (57)* | 17 (19)* | <0.0001 |
Insulin sensitivity (ml/min per m2) | 411 (76)* | 380 (77)* | <0.0001 |
Data are median (interquartile range) or n unless otherwise indicated.
§Progressors vs. nonprogressors.
*P < 0.01 vs. baseline. ns, not significant.