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Examples of the effect of UTP on lumbosacral bladder neuron responses to ATP. A fraction (8 of 21) of bladder neurons was sensitized by UTP, showing evoked AP firing (A) or increased frequency of APs (B) relative to the response to ATP before UTP application to the same cell. Other neurons (13 of 21) did not exhibit changes in response to ATP after UTP application (C, D).
