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. Author manuscript; available in PMC: 2010 Feb 25.
Published in final edited form as: Cell. 2009 Jul 10;138(1):129–145. doi: 10.1016/j.cell.2009.05.047

Figure 2. Signal-independent transcription initiation of PRG-Is.

Figure 2

(A) BMMΦs were analyzed by ChIP (Pol II). (B) Pol II values (Figure 2A) were graphed against H3Ac or H3K4me3 values (Figure 1D, E). (C) BMMΦs were analyzed by ChIP (S5P Pol II, S2P Pol II). (D) WT and MyD88/TRIF−/− BMMΦs were analyzed by ChIP (S5P Pol II, S2P Pol II). (E, F) WT and MyD88/TRIF−/− BMMΦs were stimulated for 1 hour with LPS and analyzed by ChIP (Pol II, S5P Pol II). (G) BMMΦs were analyzed by ChIP (Sp1). (H) Mouse embryonic fibroblasts (MEFs) were transfected with siRNA oligos targeted to Sp1 (d1,d2) or a scrambled control oligo (sc) and analyzed by ChIP (S5P Pol II). (A–H) Data are representative of 3 or more independent experiments. Error bars represent mean+/−SEM.