Table 1.
Concentration of plasma and brain non-esterified fatty acids, and brain acyl-CoA in control and LPS-treated rats
Plasma Non-esterified Fatty Acid (nmol/ml) |
Brain Non-esterified Fatty Acid (nmol/g) |
Brain Acyl-CoA (nmol/g) |
||||
---|---|---|---|---|---|---|
Fatty Acid | Control | LPS | Control | LPS | Control | LPS |
Palmitate (16:0) |
266.1 ± 95.6 | 283.1 ± 53.7 | 25.9 ± 10.3 | 26.8 ± 5.7 | 29.0 ± 6.7 | 34.6 ± 10.0 |
Stearate (18:0) |
72.2 ± 42.6 | 81.0 ± 21.3 | 77.7 ± 12.3 | 60.9 ± 17.7 | 5.0 ± 3.8 | 8.4 ± 4.7 |
Oleate (18:1n-9) |
221.4 ± 82.8 | 214.3 ± 51.0 | 62.0 ± 10.1 | 65.2 ± 9.1 | 27.6 ± 8.0 | 30.4 ± 8.7 |
Linoleate (18:2n-6) |
277.2 ± 62.6 | 296.3 ± 77.3 | 6.2 ± 2.7 | 8.3 ± 3.0 | 10.4 ± 3.0 | 14.3 ± 10.2 |
Arachidonate (20:4n-6) |
20.9 ± 7.3 | 26.2 ± 7.0 | 4.6 ± 0.5 | *15.8 ± 5.4 | 1.8 ± 0.8 | 1.3 ± 1.0 |
Docosahexaenoate (22:6n-3) |
9.4 ± 4.6 | 9.1 ± 3.9 | 4.2 ± 0.8 | 5.3 ± 1.2 | 1.5 ± 0.8 | 2.1 ± 0.7 |
Values are means ± SD (n = 7).
p < 0.05, differs from control mean.