Table 2.
Incorporation coefficients (), net incorporation rates from brain docosahexaenoyl-CoA (JFA,i), and fractional turnover rates (FFA,i) of DHA in different rain phospholipid pools in control and LPS-treated rats
Incorporation Coefficient | Incorporation Rate | Fractions Turnover Rate | ||||
---|---|---|---|---|---|---|
(ml/g × s, ×10−5) | JFA,i (nmol/g × s, × 10−3) | FFA, i (%/h) | ||||
Phospholipid | Control | LPS | Control | LPS | Control | LPS |
PtdEtn | 4.5 ± 1.3 | 4.9 ± 0.6 | 14.2 ± 4.0 | 14.9 ± 1.8 | 3.5 ± 1.0 | 3.6 ± 0.5 |
PlsEtn | 1.1 ± 0.4 | 1.4 ± 0.9 | 3.5 ± 1.3 | 4.3 ± 2.7 | 0.9 ± 0.3 | 1.1 ± 0.7 |
PtdIns | 2.7 ± 0.6 | 2.5 ± 0.7 | 8.6 ± 1.8 | 7.7 ± 2.1 | 16.3 ± 3.5 | 14.7 ± 3.9 |
PtdSer | 1.5 ± 0.5 | 1.3 ± 0.4 | 4.7 ± 1.6 | 4.0 ± 1.3 | 1.1 ± 0.4 | 1.0 ± 0.3 |
PtdCho | 4.4 ± 1.2 | 4.5 ± 0.9 | 13.8 ± 3.9 | 13.5 ± 2.6 | 8.6 ± 2.4 | 8.4 ± 1.6 |
PlsCho | 0.7 ± 0.3 | 0.5 ± 0.2 | 2.0 ± 0.9 | 1.6 ± 0.5 | 6.4 ± 2.9 | 5.2 ± 1.5 |
Values are means ± SD (n = 7).
Abbreviations: PtdEtn, phosphatidylethanolamine; PlsEtn, plasmenylethanolamine; PtdIns, phosphatidylinositol; PtdSer, phosphatidylserine; PtdCho, phosphatidylcholine; PlsCho, plasmenylcholine.