Table 2.
n | Body weight (kg) | Heart weight (g) | Risk zone volume (cm3) | Infarct volume (cm3) | I/R (%) | |
---|---|---|---|---|---|---|
Control | 6 | 2.3 ± 0.1 | 7.2 ± 0.2 | 1.24 ± 0.06 | 0.47 ± 0.03 | 38.0 ± 2.1 |
AMP579 | 4 | 2.5 ± 0.0 | 8.5 ± 0.2 | 1.22 ± 0.13 | 0.16 ± 0.04* | 12.9 ± 2.2* |
PSB1115 | 4 | 2.4 ± 0.0 | 7.8 ± 0.4 | 1.48 ± 0.10 | 0.49 ± 0.05 | 32.6 ± 1.8 |
NECA | 4 | 2.4 ± 0.2 | 7.5 ± 0.4 | 1.45 ± 0.10 | 0.21 ± 0.05* | 14.3 ± 0.3* |
AMP579 + PSB1115 | 6 | 2.5 ± 0.1 | 8.1 ± 0.2 | 1.47 ± 0.18 | 0.49 ± 0.09 | 32.2 ± 3.1 |
NECA + PSB1115 | 6 | 2.5 ± 0.0 | 8.5 ± 0.2 | 1.43 ± 0.14 | 0.55 ± 0.07 | 38.7 ± 2.4 |
Values are mean ± SEM
see Table 1; I/R infarction as a percentage of risk zone, n number of animals
Statistical significance of difference between experimental and control groups:
P < 0.05