TABLE II.
Summary of predictability of Random Forests and RuleFit with five-fold cross-validation using 17 risk factors and 287 tagSNPs
| Random Forests |
RuleFit |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Data set 1 |
Data set 2 |
Data set 1 |
Data set 2 |
|||||||||
| AUC | Sensitivity (%) |
Specificity (%) |
AUC | Sensitivity (%) |
Specificity (%) |
AUC | Sensitivity (%) |
Specificity (%) |
AUC | Sensitivity (%) |
Specificity (%) |
|
| Subset 1 | 0.746 | 80.8 | 60.0 | 0.843 | 89.1 | 61.5 | 0.690 | 71.2 | 60.0 | 0.746 | 73.9 | 61.5 |
| Subset 2 | 0.746 | 70.7 | 71.0 | 0.675 | 71.2 | 60.0 | 0.681 | 73.2 | 61.3 | 0.614 | 71.2 | 50.0 |
| Subset 3 | 0.778 | 79.6 | 61.1 | 0.718 | 74.5 | 61.9 | 0.667 | 70.4 | 61.1 | 0.696 | 76.5 | 61.9 |
| Subset 4 | 0.752 | 75.0 | 61.5 | 0.718 | 71.9 | 69.2 | 0.692 | 68.8 | 65.4 | 0.739 | 78.1 | 61.5 |
| Subset 5 | 0.777 | 77.5 | 71.4 | 0.766 | 81.3 | 68.2 | 0.786 | 85.0 | 71.4 | 0.665 | 68.8 | 59.1 |
| Mean | 0.760 | 76.7 | 65.0 | 0.744 | 77.6 | 64.2 | 0.703 | 73.7 | 63.8 | 0.692 | 73.7 | 58.8 |
| STD | 0.016 | 4.0 | 5.7 | 0.064 | 7.6 | 4.2 | 0.047 | 6.5 | 4.7 | 0.054 | 3.8 | 5.1 |
SNP, single nucleotide polymorphism; AUC, area under the curve.