Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Feb 22;188(4):565–579. doi: 10.1083/jcb.200908055

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 Owald et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 10. — Defective DLiprin-α localization in dsyd-1 mutants. (A–C) DLiprin-α^GFP/BRP-short^mStraw co-imaging in control (A), dsyd-1 (B), and dsyd-1^rescue (C) are shown. The localization of DLiprin-α is changed at dsyd-1 mutant NMJs, but is rescued by reexpression of UAS–dsyd-1^cDNA in motoneurons. Bars, 2 µm and 500 nm (insets). Arrowheads indicate AZs marked by BRP and arrows indicate ectopic DLiprin-α in dsyd-1 mutants. (D–F) DSyd-1 localizes to AZs in control (D), dliprin-α (E), and brp (F) animals. (G) Model of AZ assembly. Yellow arrow, DSyd-1 regulates DLiprin-α early in assembly; green arrow, DSyd-1 regulates GluR field size; gray arrow, DSyd-1 binds BRP and regulates BRP supply. Bars: (A, top): 2 µm; (A, bottom) 500 nm; (F) 2 µm.