Table 1.
GO categories significantly enriched for β-actin target genes
| GO category | β-Actintarget genes | p valuea(EASE score) |
|---|---|---|
| Apoptosis (GO:0006915) | 17 | 0.028 |
| Cell surface receptor linked | ||
| Signal transduction (GO:0007166) | 60 | 0.0054 |
| Response to external stimulus(GO:0009605) | 64 | 0.013 |
| Chemotaxis (GO:0006935) | 15 | 0.0029 |
| Immune response (GO:0006955) | 36 | 0.0036 |
| Cell cycle (GO:0007049) | 29 | 0.0081 |
| Protein biosynthesis(GO:0006412) | 34 | 0.0041 |
| Protein modification(GO:0006464) | 46 | 0.0086 |
| Catabolism (GO:0009056) | 53 | 0.0018 |
| Biosynthesis (GO:0009058) | 51 | 0.0036 |
| RNA biosynthetic process(GO:0032774) | 28 | 0.0046 |
| RNA processing (GO:0006396) | 23 | 0.0027 |
| DNA repair (GO:0006281) | 11 | 0.0012 |
| DNA replication (GO:0006260) | 14 | 0.0052 |
| Ion channel activity(GO:0005216) | 46 | 0.0025 |
| Ion transport (GO:0006811) | 28 | 0.0093 |
| Cell motility (GO:0048870) | 15 | 0.0053 |
| Cell growth and/or maintenance(GO:0009987) | 87 | 0.0062 |
| Cell differentiation (GO:0043697) | 12 | 0.0039 |
| Cell development (GO:0007275) | 72 | 0.0076 |
a The threshold of EASE score, a modified Fisher exact p value, for gene-enrichment analysis. Usually, the p value is ≤0.05 to be considered strongly enriched in the annotation categories.