Figure 4.

Binding of ¹²⁵I-SLT-1A^IYSNKLM to 518-A2 cells. (A) Specific binding (white squares), total binding (black squares), and non-specific binding (white triangles) of ¹²⁵I-SLT-1A^IYSNKLM to 518-A2 cells at 4°C. (B) Displacement curves in which 518-A2 cells were treated with 45 nM of ¹²⁵I-SLT-1A^IYSNKLM in the presence of increasing concentrations of either unlabeled SLT-1A^IYSNKLM (black circles) or a synthetic 16-residue peptide containing the inserted 7-amino acid peptide ligand (HHHIYSNKLMASRVAR) (black squares). Data points represent the s.e.m. of experiments performed in triplicate.